Here’s a list of the Big 5 US Publishing Houses, their submission requirements and links to submission details. I’ve also included at the end of the list two smaller US Publishers that I have submitted to in the past (received real feedback!) I thought they would serve as good examples of what’s out there if you decide to try the smaller publishers.
So on not so good authority, this is totally what your editor (and beta-reader) goes through while editing your novel for the first time. Spare a somber thought for those who do it for free.